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Merck

BMP4

bone morphogenetic protein 4

Synonyms:
BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
Species:
Human BMP4 (652), Mouse Bmp4 (12159), Rat Bmp4 (25296), dog BMP4 (490695), Domestic Rabbit BMP4 (100009569), naked mole-rat Bmp4 (101711207), domestic guinea pig Bmp4 (100733516), sheep BMP4 (443502), Goat BMP4 (100860789), cow BMP4 (407216) ...More
UniProtKB ID:
P12644, Q9UM80
Gene ID:
  • Human(652) Summary: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq, Jul 2008]
  • Mouse(12159) bone morphogenetic protein 4
  • Rat(25296) bone morphogenetic protein 4
  • dog(490695) bone morphogenetic protein 4
  • Domestic Rabbit(100009569) bone morphogenetic protein 4
  • naked mole-rat(101711207) bone morphogenetic protein 4
  • domestic guinea pig(100733516) bone morphogenetic protein 4
  • sheep(443502) bone morphogenetic protein 4
  • Goat(100860789) bone morphogenetic protein 4
  • cow(407216) bone morphogenetic protein 4
  • Horse(100034048) bone morphogenetic protein 4
  • Zebrafish(30612) bone morphogenetic protein 4
  • chicken(396165) bone morphogenetic protein 4
  • domestic cat(101100311) bone morphogenetic protein 4

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ELISA

Product Number
Description
Species
RAB0030
Human BMP-4 ELISA Kit, for cell and tissue lysates,
Species
human
RAB0029
Human BMP-4 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
MAB1049
Anti-Bone Morphogenetic Protein 4 Antibody, clone 3H2, clone 3H2, Chemicon®, from mouse,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry
western blot