BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
Synonyms:
BCL11A-L, BCL11A-S, BCL11A-XL, BCL11a-M, CTIP1, EVI9, HBFQTL5, ZNF856
Species:
Human BCL11A (53335), Mouse Bcl11a (14025), Rat Bcl11a (305589), Domestic Rabbit BCL11A (100355522), sheep BCL11A (101119124), domestic guinea pig Bcl11a (100734801), dog BCL11A (481381), chicken BCL11A (421199), cow BCL11A (538680), domestic cat BCL11A (101098704)
UniProtKB ID:
Gene ID:
- Human(53335) Summary: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14025) B cell CLL/lymphoma 11A (zinc finger protein)
- Rat(305589) B-cell CLL/lymphoma 11A (zinc finger protein)
- Domestic Rabbit(100355522) B-cell CLL/lymphoma 11A (zinc finger protein)
- sheep(101119124) B-cell CLL/lymphoma 11A (zinc finger protein)
- domestic guinea pig(100734801) B-cell CLL/lymphoma 11A (zinc finger protein)
- dog(481381) B-cell CLL/lymphoma 11A (zinc finger protein)
- chicken(421199) B-cell CLL/lymphoma 11A (zinc finger protein)
- cow(538680) B-cell CLL/lymphoma 11A (zinc finger protein)
- domestic cat(101098704) B-cell CLL/lymphoma 11A (zinc finger protein)
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