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Merck

AZIN1

antizyme inhibitor 1

Synonyms:
OAZI, OAZIN, ODC1L
Species:
UniProtKB ID:
Gene ID:
  • Human(51582) Summary: Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. Ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein encoded by this gene is highly similar to ODC. It binds to ODC antizyme and stabilizes ODC, thus inhibiting antizyme-mediated ODC degradation. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(54375) antizyme inhibitor 1
  • Rat(58961) antizyme inhibitor 1
  • chicken(420254) antizyme inhibitor 1
  • naked mole-rat(101721609) antizyme inhibitor 1
  • domestic guinea pig(100729426) antizyme inhibitor 1
  • dog(475058) antizyme inhibitor 1
  • domestic cat(101100539) antizyme inhibitor 1
  • sheep(101122702) antizyme inhibitor 1
  • Horse(100056267) antizyme inhibitor 1
  • cow(532835) antizyme inhibitor 1

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