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Merck

ATP6V1H

ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

Synonyms:
MSTP042, NBP1, SFD, SFDalpha, SFDbeta, VMA13
Species:
Human ATP6V1H (51606), Mouse Atp6v1h (108664), Rat Atp6v1h (297797), naked mole-rat Atp6v1h (101710987), domestic guinea pig Atp6v1h (100716527), sheep ATP6V1H (101113504), dog ATP6V1H (486953), cow ATP6V1H (282657), Zebrafish atp6v1h (286779), chicken ATP6V1H (426199)
UniProtKB ID:
Q9UI12, B3KMR0, Q6PK44, Q9H3E3, Q9Y300
Gene ID:
  • Human(51606) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(108664) ATPase, H+ transporting, lysosomal V1 subunit H
  • Rat(297797) ATPase, H+ transporting, lysosomal V1 subunit H
  • naked mole-rat(101710987) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
  • domestic guinea pig(100716527) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
  • sheep(101113504) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
  • dog(486953) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
  • cow(282657) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
  • Zebrafish(286779) ATPase, H+ transporting, lysosomal, V1 subunit H
  • chicken(426199) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
  • domestic cat(101095225) ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

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