ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Synonyms:
BIG2, PVNH2, dJ1164I10.1
Species:
Human ARFGEF2 (10564), Mouse Arfgef2 (99371), Rat Arfgef2 (296380), naked mole-rat Arfgef2 (101706311), dog ARFGEF2 (477256), domestic cat ARFGEF2 (101082556), domestic guinea pig Arfgef2 (100724838), sheep ARFGEF2 (101116164), Horse ARFGEF2 (100071351), cow ARFGEF2 (539295) ...More
UniProtKB ID:
Gene ID:
- Human(10564) Summary: ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
- Mouse(99371) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- Rat(296380) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- naked mole-rat(101706311) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- dog(477256) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- domestic cat(101082556) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- domestic guinea pig(100724838) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- sheep(101116164) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- Horse(100071351) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- cow(539295) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- chicken(419211) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- Zebrafish(100334572) ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
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