APLP1
amyloid beta (A4) precursor-like protein 1
Synonyms:
APLP
Species:
Human APLP1 (333), Mouse Aplp1 (11803), Rat Aplp1 (502317), domestic guinea pig Aplp1 (100725457), Horse APLP1 (100060016), naked mole-rat Aplp1 (101706550), sheep APLP1 (101105352), cow APLP1 (513154), domestic cat APLP1 (101097529), dog APLP1 (476478)
UniProtKB ID:
Gene ID:
- Human(333) Summary: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11803) amyloid beta (A4) precursor-like protein 1
- Rat(502317) amyloid beta (A4) precursor-like protein 1
- domestic guinea pig(100725457) amyloid beta (A4) precursor-like protein 1
- Horse(100060016) amyloid beta (A4) precursor-like protein 1
- naked mole-rat(101706550) amyloid beta (A4) precursor-like protein 1
- sheep(101105352) amyloid beta (A4) precursor-like protein 1
- cow(513154) amyloid beta (A4) precursor-like protein 1
- domestic cat(101097529) amyloid beta (A4) precursor-like protein 1
- dog(476478) amyloid beta (A4) precursor-like protein 1
- Zebrafish(404233) amyloid beta (A4) precursor-like protein 1
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