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Merck

AGTR1

angiotensin II receptor, type 1

Synonyms:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Species:
Human AGTR1 (185), naked mole-rat Agtr1 (101714068), Domestic Rabbit AGTR1 (100009164), domestic guinea pig Agtr1 (100192325), sheep AGTR1 (443107), dog AGTR1 (403836), chicken AGTR1 (396065), cow AGTR1 (281607), domestic cat AGTR1 (101082936)
UniProtKB ID:
P30556, Q13725
Gene ID:
  • Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • naked mole-rat(101714068) angiotensin II receptor, type 1
  • Domestic Rabbit(100009164) angiotensin II receptor, type 1
  • domestic guinea pig(100192325) angiotensin II receptor, type 1
  • sheep(443107) angiotensin II receptor, type 1
  • dog(403836) angiotensin II receptor, type 1
  • chicken(396065) angiotensin II receptor, type 1
  • cow(281607) angiotensin II receptor, type 1
  • domestic cat(101082936) angiotensin II receptor, type 1

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Small Molecule - Antagonist

Product Number
Description
Species
PHR1602
Losartan Potassium, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1370462
Losartan potassium, United States Pharmacopeia (USP) Reference Standard,
Species
human
PHR1315
Valsartan, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
BP1248
Candesartan cilexetil, British Pharmacopoeia (BP) Reference Standard,
Species
human
1347700
Irbesartan, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
AB15552
Anti-AT1 Receptor Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot