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Merck

ADRA1A

adrenoceptor alpha 1A

Synonyms:
ADRA1C, ADRA1L1, ALPHA1AAR
Species:
Human ADRA1A (148), Mouse Adra1a (11549), Rat Adra1a (29412), cow ADRA1A (282134), domestic cat ADRA1A (101098375), domestic guinea pig Adra1a (100135474), dog ADRA1A (403866), sheep ADRA1A (100169940), chicken ADRA1A (428203), naked mole-rat Adra1a (101712485)
UniProtKB ID:
P35348, A8K0I3, B0ZBD1, B0ZBD2, B0ZBD4, B0ZBD5, B0ZBD6, B0ZBD8
Gene ID:
  • Human(148) Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
  • Mouse(11549) adrenergic receptor, alpha 1a
  • Rat(29412) adrenoceptor alpha 1A
  • cow(282134) adrenergic, alpha-1A-, receptor
  • domestic cat(101098375) adrenoceptor alpha 1A
  • domestic guinea pig(100135474) adrenergic receptor, alpha 1a
  • dog(403866) adrenoceptor alpha 1A
  • sheep(100169940) adrenoceptor alpha 1A
  • chicken(428203) adrenoceptor alpha 1A
  • naked mole-rat(101712485) adrenoceptor alpha 1A
  • Domestic Rabbit(100009237) adrenoceptor alpha 1A

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Small Molecule - Agonist

Product Number
Description
Species
PHR1017
Phenylephrine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
E4375
(−)-Epinephrine (+)-bitartrate salt, solid,
Species
human
A0937
(±)-Norepinephrine (+)-bitartrate salt, ,
Species
human
PHR1509
Epinephrine Bitartrate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
PHR1721
Terazosin Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
BP876
Tamsulosin hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
PHR1524
Tamsulosin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
62320
(±)-α-Lipoic acid, ≥98.0%,
Species
rat, human
Y0001426
Carvedilol for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human

Proteins

Product Number
Description
Species
HTS087M
ChemiScreen Recombinant HumanMembrane Preparation

α1A Adrenergic Receptor, Human alpha1A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Species
human