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Merck

ADORA3

adenosine A3 receptor

Synonyms:
A3AR, AD026, bA552M11.5
Species:
UniProtKB ID:
Gene ID:
  • Human(140) Summary: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11542) adenosine A3 receptor
  • Rat(25370) adenosine A3 receptor
  • dog(403805) adenosine A3 receptor
  • Domestic Rabbit(100008725) adenosine A3 receptor
  • sheep(443330) adenosine A3 receptor
  • cow(780806) adenosine A3 receptor
  • naked mole-rat(101697269) adenosine A3 receptor
  • chicken(373956) adenosine A3 receptor
  • domestic cat(101094689) adenosine A3 receptor
  • domestic guinea pig(100725432) adenosine A3 receptor

Custom & Knockdown Gene Products

Small Molecule - Agonist

Product Number
Description
Species
Adenosine, United States Pharmacopeia (USP) Reference Standard,
Species
human
Adenosine, European Pharmacopoeia (EP) Reference Standard,
Species
human
Adenosine, phyproof® Reference Substance,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Tyramine hydrochloride, ≥98%,
Species
human
Caffeine for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Caffeine melting point standard, United States Pharmacopeia (USP) Reference Standard,
Species
human
Caffeine, European Pharmacopoeia (EP) Reference Standard,
Species
human
Caffeine, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168), Chemicon®, from rabbit,
Species Reactivity
rat
Application
ELISA
immunocytochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
α-Naphthoflavone, ≥98%,
Species
human, rat
Caffeine, anhydrous, 99%, FCC, FG,
Species
mouse, human, rat
Caffeine, anhydrous, tested according to Ph. Eur.,
Species
mouse, human, rat
Caffeine, Sigma Reference Standard, vial of 250 mg,
Species
mouse, human, rat
Theophylline, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Theophylline, anhydrous, ≥99%, powder,
Species
mouse, human, rat