ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide
Synonyms:
ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR
Species:
Human ADH5 (128), Mouse Adh5 (11532), Rat Adh5 (100145871), domestic guinea pig Adh5 (100719427), Domestic Rabbit ADH5 (100009307), sheep ADH5 (101112223), cow ADH5 (505515), domestic cat ADH5 (101101307), dog ADH5 (609781), chicken ADH5 (422705) ...More
UniProtKB ID:
Gene ID:
- Human(128) Summary: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]
- Mouse(11532) alcohol dehydrogenase 5 (class III), chi polypeptide
- Rat(100145871) alcohol dehydrogenase 5 (class III), chi polypeptide
- domestic guinea pig(100719427) alcohol dehydrogenase 5 (class III), chi polypeptide
- Domestic Rabbit(100009307) alcohol dehydrogenase 5 (class III), chi polypeptide
- sheep(101112223) alcohol dehydrogenase 5 (class III), chi polypeptide
- cow(505515) alcohol dehydrogenase 5 (class III), chi polypeptide
- domestic cat(101101307) alcohol dehydrogenase 5 (class III), chi polypeptide
- dog(609781) alcohol dehydrogenase 5 (class III), chi polypeptide
- chicken(422705) alcohol dehydrogenase 5 (class III), chi polypeptide
- Zebrafish(116517) alcohol dehydrogenase 5
- naked mole-rat(101717353) alcohol dehydrogenase 5 (class III), chi polypeptide
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