ACVR1B
activin A receptor, type IB
Synonyms:
ACTRIB, ACVRLK4, ALK4, SKR2
Species:
Human ACVR1B (91), Mouse Acvr1b (11479), Rat Acvr1b (29381), chicken ACVR1B (768878), sheep ACVR1B (443254), naked mole-rat Acvr1b (101709452), dog ACVR1B (486537), sheep ACVR1B (101113836), cow ACVR1B (539315), Horse ACVR1B (100062619) ...More
UniProtKB ID:
Gene ID:
- Human(91) Summary: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
- Mouse(11479) activin A receptor, type 1B
- Rat(29381) activin A receptor, type IB
- chicken(768878) activin A receptor, type IB
- sheep(443254) activin A receptor, type IB
- naked mole-rat(101709452) activin A receptor, type IB
- dog(486537) activin A receptor, type IB
- sheep(101113836) activin A receptor, type IB
- cow(539315) activin A receptor, type IB
- Horse(100062619) activin A receptor, type IB
- Zebrafish(30183) activin A receptor, type IB
- domestic cat(101097654) activin A receptor, type IB
- domestic guinea pig(100733441) activin A receptor, type IB
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