ACHE
acetylcholinesterase
Synonyms:
ACEE, ARACHE, N-ACHE, YT
Species:
Human ACHE (43), Mouse Ache (11423), Rat Ache (83817), domestic guinea pig Ache (100422792), sheep ACHE (101123006), cow ACHE (540446), domestic cat ACHE (493674), Zebrafish ache (114549), chicken ACHE (396388), naked mole-rat Ache (101705724)
UniProtKB ID:
Gene ID:
- Human(43) Summary: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]
- Mouse(11423) acetylcholinesterase
- Rat(83817) acetylcholinesterase
- domestic guinea pig(100422792) acetylcholinesterase
- sheep(101123006) acetylcholinesterase
- cow(540446) acetylcholinesterase
- domestic cat(493674) acetylcholinesterase
- Zebrafish(114549) acetylcholinesterase
- chicken(396388) acetylcholinesterase
- naked mole-rat(101705724) acetylcholinesterase
- dog(489828) acetylcholinesterase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Acetylcholinesterase Antibody, clone AE-1, clone AE-1, Chemicon®, from mouse,
Species Reactivity
bovine, canine, chicken, guinea pig, human, monkey
Application
ELISA
immunohistochemistry
immunoprecipitation (IP)
immunohistochemistry
immunoprecipitation (IP)
Small Molecule - Inhibitor
Product Number
Description
Species
Kits
Product Number
Description
Species
Acetylcholinesterase Activity Assay Kit, sufficient for 100 colorimetric tests,
Species
mouse, human
Proteins
Product Number
Description
Species
Acetylcholinesterase from human erythrocytes, buffered aqueous solution, ≥500 units/mg protein (BCA),
Species
human