ACE2
angiotensin I converting enzyme 2
Synonyms:
ACEH
Species:
Human ACE2 (59272), Mouse Ace2 (70008), Rat Ace2 (302668), Domestic Rabbit ACE2 (100327258), sheep ACE2 (101103622), cow ACE2 (509235), chicken ACE2 (418623), domestic cat ACE2 (554349), Zebrafish ace2 (492331), naked mole-rat Ace2 (101697829) ...More
UniProtKB ID:
Gene ID:
- Human(59272) Summary: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
- Mouse(70008) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- Rat(302668) angiotensin I converting enzyme 2
- Domestic Rabbit(100327258) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- sheep(101103622) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- cow(509235) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- chicken(418623) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- domestic cat(554349) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- Zebrafish(492331) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- naked mole-rat(101697829) angiotensin I converting enzyme 2
- dog(480847) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
- domestic guinea pig(100302675) angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
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Small Molecule - Substrate
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