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Key Documents

SML2557

Sigma-Aldrich

Aminopyridine 2

≥98% (HPLC)

Synonym(s):

1-((6-Aminopyridin-3-yl)methyl)-3-(4-bromophenyl)urea

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About This Item

Empirical Formula (Hill Notation):
C13H13BrN4O
CAS Number:
Molecular Weight:
321.17
UNSPSC Code:
12352200
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

NC1=CC=C(CNC(NC2=CC=C(Br)C=C2)=O)C=N1

Biochem/physiol Actions

Aminopyridine 2 (1-((6-aminopyridin-3-yl)methyl)-3-(4-bromophenyl)urea) is an orally available, potent and selective irreversible inhibitor of myeloperoxidase (MPO) that blocks vasomotor dysfunction in rat aortic rings. Aminopyridine 2 inhibits myeloperoxidase in a mouse model of peritonitis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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