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D16401

Sigma-Aldrich

1,12-Diaminododecane

98%

Synonym(s):

1,12-Dodecanediamine, Dodecamethylenediamine

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About This Item

Linear Formula:
NH2(CH2)12NH2
CAS Number:
2783-17-7
Molecular Weight:
200.36
Beilstein:
1742765
EC Number:
220-489-6
MDL number:
MFCD00008155
UNSPSC Code:
12352100
PubChem Substance ID:
24893504
NACRES:
NA.22

Assay

98%

form

flakes

mp

67-69 °C (lit.)

SMILES string

NCCCCCCCCCCCCN

InChI

1S/C12H28N2/c13-11-9-7-5-3-1-2-4-6-8-10-12-14/h1-14H2

InChI key

QFTYSVGGYOXFRQ-UHFFFAOYSA-N

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Application

Feedstock for polymer synthesis. Source of twelve carbon chain for medicinal drugs.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H314,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

311.0 °F - closed cup

Flash Point(C)

155 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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R Hochreiter et al.
Naunyn-Schmiedeberg's archives of pharmacology, 361(3), 235-246 (2000-03-24)
A series of diamines with the general structure NH2(CH2)xNH2, x=2-12, was tested for their potential effects on cell proliferation of cultured rat C6 glioma cells in comparison to natural polyamines. Long chain diamines reduced cell number after 48 h in
Michelle J Pisani et al.
Dalton transactions (Cambridge, England : 2003), 39(8), 2078-2086 (2010-02-12)
A simpler method for the purification of cucurbit[10]uril (Q[10]) from the Q[10].Q[5] inclusion complex is reported. 1,12-Diaminododecane was used to displace Q[5], as opposed to the synthetic melamine derivative currently used. The binding of trans-[{PtCl(NH(3))(2)}(2)(micro-NH(2)(CH(2))(8)NH(2))](2+) (CT008) and [{Ru(phen)(2)}(2)(micro-bb(5))](4+) {phen =
A Sintov et al.
Biomaterials, 16(6), 473-478 (1995-04-01)
Chondroitin sulphate was cross-linked with 1,12-diaminododecane to give a series of cross-linked products with reduced water solubility. Since the water solubility of the modified polymers is low, their chemical characterization is complicated. A new method based on the adsorption of
E Dziembor-Gryszkiewicz et al.
Biochemistry international, 6(5), 627-633 (1983-05-01)
The acid phosphatase [EC 3.1.3.2] from human prostate gland is very unstable glycoprotein. To stabilize the enzyme cross-linking reaction with diamines was adopted. The carboxyl groups of the enzyme were activated with 1-ethyl-(3-dimethylaminopropyl)-carbodiimide and then treated with diamines of H2N-(CH2)n-NH2
Michelle Henderson Pozzi et al.
Biochemistry, 48(7), 1508-1516 (2009-02-10)
Mammalian polyamine oxidases (PAOs) catalyze the oxidation of N1-acetylspermine and N1-acetylspermidine to produce N-acetyl-3-aminopropanaldehyde and spermidine or putrescine. Structurally, PAO is a member of the monoamine oxidase family of flavoproteins. The effects of pH on the kinetic parameters of mouse
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