B3023

Bumetanide

≥98% (TLC), powder, Na⁺/K⁺/Cl⁻ cotransporter inhibitor

• Synonym(s): 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid
• Empirical Formula (Hill Notation): C₁₇H₂₀N₂O₅S
• CAS Number: 28395-03-1
• Molecular Weight: 364.42
• EC Number: 249-004-6
• MDL number: MFCD00078949
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278265
• NACRES: NA.77

Properties

• product name: Bumetanide, ≥98%
• Assay: ≥98%
• form: powder
• originator: Roche
• SMILES string: CCCCNc1cc(cc(c1Oc2ccccc2)S(N)(=O)=O)C(O)=O
• InChI: 1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)
• InChI key: MAEIEVLCKWDQJH-UHFFFAOYSA-N
• Gene Information: human ... SLC12A1(6557)

Description

Biochem/physiol Actions

Inhibitor of Na⁺/K⁺/Cl^- cotransporter.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves