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PHL80356

Astilbin

phyproof® Reference Substance

Synonym(s):

Dihydroquercetin 3-rhamnoside, Taxifolin 3-rhamnoside

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About This Item

Empirical Formula (Hill Notation):
C21H22O11
CAS Number:
29838-67-3
Molecular Weight:
450.39
MDL number:
MFCD20274680
UNSPSC Code:
41116107
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥95.0% (HPLC)

manufacturer/tradename

PhytoLab

format

neat

storage temp.

2-8°C

SMILES string

O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(O)C=C3)[C@H]1O[C@@]4([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4

InChI

1S/C21H22O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-26,28-29H,1H3/t7-,15-,17+,18+,19-,20+,21-/m0/s1

InChI key

ZROGCCBNZBKLEL-MFSALPCASA-N

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General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations. Immunosuppresive. Antiproliferative.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
68785
74000371

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Meiyun Shi et al.
The Journal of pharmacy and pharmacology, 72(8), 1061-1071 (2020-04-30)
The purpose of this study is to reveal the pharmacokinetic profiles of astilbin with various doses in rats and investigate the oral absolute bioavailability and tissue distribution of astilbin after oral administration. Wistar rats were orally administered astilbin 12, 24 mg/kg
Qianni Duan et al.
Journal of ethnopharmacology, 249, 112405-112405 (2019-11-20)
The Chinese Herbal Prescription JieZe-1(JZ-1), added and subtracted from Yihuang Decoction, a famous formula in the 12th year of Kangxi in Qing Dynasty, has a clear effect on Genital Herpes (GH) and no obvious adverse reactions occur clinically. JZ-1 also
Yu Li et al.
International immunopharmacology, 84, 106571-106571 (2020-05-16)
Ischaemic stroke is a lethal cerebrovascular disease that occurs worldwide. Astilbin is a natural flavonoid compound with various physiological activities. The purpose of this study was to investigate the neuroprotective effects of Astilbin after cerebral ischaemia reperfusion (I/R) injury. The
Dan Zheng et al.
Molecules (Basel, Switzerland), 25(20) (2020-10-21)
Astilbin and neoastilbin are two flavonoid stereoisomers. In the present study, their solubility, stability, and bioavailability were compared in a rat. The results revealed that the water solubility of astilbin and neoastilbin was 132.72 μg/mL and 217.16 μg/mL, respectively. The
Qingling Xie et al.
Journal of AOAC International, 103(1), 117-123 (2019-08-28)
Bupi Yiqi No. 1 Recipe (BPYQ), a traditional Chinese medicine formula, has been widely used as a treatment of multidrug resistance during chemotherapy in colorectal cancer and for the prevention of gastrointestinal cancer recurrence for decades. In this study, a
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