BP1210

Ritonavir

British Pharmacopoeia (BP) Reference Standard

• Sinónimos: 1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
• Fórmula empírica (notación de Hill): C₃₇H₄₈N₆O₅S₂
• Número de CAS: 155213-67-5
• Peso molecular: 720.94
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: pharmaceutical primary standard
• Quality Level: 100
• agency: BP
• API family: ritonavir
• form: solid
• shelf life: limited shelf life, expiry date on the label
• packaging: pkg of 100 mg
• manufacturer/tradename: BP
• storage condition: dry at room temperature
• color: off-white
• mp: 122-126 °C
• solubility: ethanol: soluble; isopropanol: soluble; methanol: soluble
• density: 1.239 g/cm³ at 20 °C
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• shipped in: ambient
• storage temp.: 2-8°C
• InChI: 1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
• InChI key: NCDNCNXCDXHOMX-XGKFQTDJSA-N

Descripción

General description

Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ritonavir BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Ritonavir Oral Solution

Ritonavir Tablets

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332
• pcodes: P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable