SML1370

A-779 trifluoroacetate salt

≥98% (HPLC)

• Sinónimos: A779 trifluoroacetate salt, Asp1-Arg2-Val3-Tyr4-Ile5-His6-D-Ala7, D-Ala7-Ang-(1-7), DRVYIHA (Modification: Ala-7 = D-Ala), DRVYIHa trifluoroacetate salt, H-Asp-Arg-Val-Tyr-Ile-His-D-Ala-OH trifluoroacetate salt, [7-D-ALA]-angiotensin-(1-7) trifluoroacetate salt
• Fórmula empírica (notación de Hill): C₃₉H₆₀N₁₂O₁₁ · xC₂HF₃O₂
• Número de CAS: 159432-28-7
• Peso molecular: 872.97 (free base basis)
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: lyophilized powder
• color: white to off-white
• shipped in: wet ice
• storage temp.: −20°C

Descripción

Biochem/physiol Actions

A-779 (D-Ala7-Ang-(1-7)) is a potent and selective antagonist of angiotensin (1-7), an endogenous peptide that acts through activation of a non-AT1, non-AT2 receptor, Mas, and opposes the activity of angiotensin. A-779 has an IC₅₀ of 0.3 nM for Mas with negligible affinity for either AT1R or AT2R.

This blocking angiotensin action affects cardiovascular function.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable