SBR00057

Retapamulin

≥98% (HPLC)

• Fórmula empírica (notación de Hill): C₃₀H₄₇NO₄S
• Número de CAS: 224452-66-8
• Peso molecular: 517.76
• MDL number: MFCD11045316
• UNSPSC Code: 51284706
• NACRES: NA.76

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• antibiotic activity spectrum: Gram-positive bacteria
• mode of action: protein synthesis | interferes
• storage temp.: −20°C
• InChI: 1S/C30H47NO4S/c1-7-28(4)16-24(35-25(33)17-36-22-14-20-8-9-21(15-22)31(20)6)29(5)18(2)10-12-30(19(3)27(28)34)13-11-23(32)26(29)30/h7,18-22,24,26-27,34H,1,8-17H2,2-6H3/t18-,19+,20-,21+,22?,24-,26+,27+,28-,29+,30+/m1/s1
• InChI key: STZYTFJPGGDRJD-FJJJPKKESA-N

Descripción

General description

Retapamulin (RET) is a semi-synthetic antibiotic ointment, and pleuromutilin derivative compound. The primary structural difference between pleuromutilin and retapamulin is in the C-14 side chain.

Biochem/physiol Actions

Retapamulin is a potent antibacterial agent against Gram-positive bacteria, especially against Staphylococcus aureus and S. pyogenes. It displays synergistic effects against Enterococcus faecalis in combination with streptogramin (MLS). RET initiates ribosomal arrests at the start codon and enables genes to use alternative translational sites in E. coli.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable