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P3886

Sigma-Aldrich

Poly-L-proline

suitable for ligand binding assays, Mol wt >30,000

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About This Item

Fórmula empírica (notación de Hill):
C5H9NO2
Número de CAS:
25191-13-3
Peso molecular:
115.13
MDL number:
MFCD00166364
UNSPSC Code:
12352209
PubChem Substance ID:
24898465
NACRES:
NA.26

product name

Poly-L-proline, mol wt >30,000

form

powder

mol wt

>30,000

technique(s)

ligand binding assay: suitable

color

white to light yellow

storage temp.

−20°C

SMILES string

OC(=O)C1CCCN1

InChI

1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)

InChI key

ONIBWKKTOPOVIA-UHFFFAOYSA-N

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Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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M Ashtari et al.
Journal of chromatography. A, 1265, 70-87 (2012-10-17)
Poly-proline chains and derivatives have been recently examined as the basis for new chiral stationary phases in high performance liquid chromatography. The selectivity of poly-proline has been measured for peptides with up to ten proline units. In this article, we
Christopher J Woolstenhulme et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(10), E878-E887 (2013-02-23)
Although the ribosome is a very general catalyst, it cannot synthesize all protein sequences equally well. For example, ribosomes stall on the secretion monitor (SecM) leader peptide to regulate expression of a downstream gene. Using a genetic selection in Escherichia
Biochemistry. Getting past polyproline pauses.
Allen R Buskirk et al.
Science (New York, N.Y.), 339(6115), 38-39 (2013-01-05)
Helena Bysell et al.
Langmuir : the ACS journal of surfaces and colloids, 25(1), 522-528 (2008-12-09)
The relative importance of electrostatic and nonelectrostatic interactions in peptide-microgel systems was evaluated by micromanipulator-assisted light microscopy, confocal microscopy, and circular dichroism. For this purpose, the interaction of various homopolypeptides with lightly cross-linked polyelectrolyte gel particles ( approximately 70 microm
Noemi G Mirkin et al.
Biopolymers, 97(10), 789-794 (2012-07-19)
Although subsequent studies have provided extensive support for the 1968 Tiffany and Krimm proposal (Biopolymers 6, 1379) that the polyproline II (PPII) conformation is a significant component of the structure of unordered polypeptide chains, two issues are still not fully
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