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L4263

Sigma-Aldrich

Sodium DL-lactate solution

BioReagent, syrup, 60 % (w/w), synthetic, suitable for cell culture

Sinónimos:

DL-Lactic acid sodium salt

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About This Item

Fórmula lineal:
CH3CH(OH)COONa
Número de CAS:
72-17-3
Peso molecular:
112.06
Beilstein/REAXYS Number:
4332999
EC Number:
200-772-0
MDL number:
MFCD00065400
UNSPSC Code:
12352207
PubChem Substance ID:
24896366
NACRES:
NA.75

biological source

synthetic

product line

BioReagent

form

syrup

concentration

27-33% (enzymatic)
60 % (w/w)

technique(s)

cell culture | mammalian: suitable

storage temp.

2-8°C

SMILES string

[Na+].CC(O)C([O-])=O

InChI

1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1

InChI key

NGSFWBMYFKHRBD-UHFFFAOYSA-M

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General description

Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). Lactate is one of the main components of Ringer′s lactate or lactated Ringer′s solution.

Application

Sodium DL-lactate solution has been used:
  • as a component in DMEM-B to prepare Dulbecco modified Eagle medium (DMEM)-C medium to evaluate the effect of medium composition on in vitro spermatogonial stem cells (SSCs) maintenance
  • as a supplement in Dulbecco′s modified Eagle′s medium-nutrient mixture F12 to obtain conditioned media of testicular macrophages
  • as a component in non-capacitation medium and TALP medium for sperm preparation and in vitro fertilization
  • in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffered synthetic oviduct fluid (SOF) media for oocyte preservation

Biochem/physiol Actions

Lactic acid is produced by lactic acid bacteria (LAB) during carbohydrate fermentation. Different microorganism synthesize different forms of lactic acid such as L(+), D(-) or DL (racemic mixture). It is preferred in food processing and preservation due to its antimicrobial property. Lactic acid is useful as a flavoring and acidifying agent.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Oocyte transport: developmental competence of bovine oocytes arrested at germinal vesicle stage by cycloheximide under air
<BIG>Hashimoto S, et al.</BIG>
Journal of Reproduction and Development, 49, 61-66 (2003)
Tumour necrosis factor-alpha released by testicular macrophages induces apoptosis of germ cells in autoimmune orchitis
<BIG>Theas MS, et al.</BIG>
Human Reproduction, 23, 1865-1872 (2008)
<BIG>Ameen SM, et al.</BIG>
Lactic Acid in the Food Industry, 20-20 (2017)
Maintenance of mouse male germ line stem cells in vitro
<BIG>Nagano M, et al.</BIG>
Biology of Reproduction, 86, 2207-2214 (2003)
Marek Nalos et al.
Critical care (London, England), 18(2), R48-R48 (2014-03-29)
Acute heart failure (AHF) is characterized by inadequate cardiac output (CO), congestive symptoms, poor peripheral perfusion and end-organ dysfunction. Treatment often includes a combination of diuretics, oxygen, positive pressure ventilation, inotropes and vasodilators or vasopressors. Lactate is a marker of
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