Saltar al contenido
Merck
Todas las fotos(5)

Documentos

L4129

Sigma-Aldrich

L-α-Lysophosphatidylcholine from egg yolk

≥99%, Type I, powder

Sinónimos:

1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(5)

About This Item

Número de CAS:
9008-30-4
EC Number:
232-715-0
MDL number:
MFCD00131444
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

egg yolk

description

zwitterionic

type

Type I

assay

≥99%

form

powder

color

white

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

¿Está buscando productos similares? Visita Guía de comparación de productos

Categorías relacionadas

Application

L-α-Lysophosphatidylcholine from egg yolk has been used:
  • as a surfactant
  • as a media supplement and in Staphylococcus aureus inhibition assay in dermatitis
  • as a demyelinating agent for nerve
  • as a component in sperm nuclei preparation buffer

Biochem/physiol Actions

Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.

Quality

Contains primarily palmitic and stearic acids.

Preparation Note

Prepared by the action of phospholipase A on egg L-α-phosphatidylcholine.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

N Farrow et al.
Scientific reports, 3, 1287-1287 (2013-02-16)
Genetic therapies for cystic fibrosis (CF) must be assessed for safety and efficacy, so testing in a non-human primate (NHP) model is invaluable. In this pilot study we determined if the conducting airways of marmosets (n = 2) could be
Lauri J Lehto et al.
Frontiers in neuroscience, 11, 433-433 (2017-08-22)
In this work a new MRI modality entitled Relaxation Along a Fictitious Field in the rotating frame of rank 4 (RAFF4) was evaluated in its ability to detect lower myelin content in lysophosphatidyl choline (LPC)-induced demyelinating lesions. The lesions were
Transplantation of human skin microbiota in models of atopic dermatitis
Myles IA, et al.
JCI insight, 1(10), 031712-031712 (2016)
Director configurations in nematic droplets with inhomogeneous boundary conditions
Prishchepa OO, et al.
Physical review. E, 72(3), 031712-031712 (2005)
Alan Brito Carneiro et al.
PloS one, 8(9), e76233-e76233 (2013-12-07)
Lysophosphatidylcholine (LPC) is the main phospholipid component of oxidized low-density lipoprotein (oxLDL) and is usually noted as a marker of several human diseases, such as atherosclerosis, cancer and diabetes. Some studies suggest that oxLDL modulates Toll-like receptor (TLR) signaling. However
Ver todos los artículos relacionados

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico