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GERPN6301

Thiourea

Cytiva RPN6301, pack of 100 g

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About This Item

Código UNSPSC:
41105323
NACRES:
NA.77

Formulario

solid

Características

wetted part: no

envase

pack of 100 g

fabricante / nombre comercial

Cytiva RPN6301

color

White

intervalo de pH

5-7

solubilidad

cold water: soluble (Soluble in cold water and hot water)
diethyl ether: soluble (Partially soluble in diethyl ether)
methanol: soluble (Easily soluble in methanol)

Descripción general

Thiourea is a chaotrope used together with urea in the IPG strip rehydration to solubilize and denature proteins, and improve the solubility of membrane proteins.

Aplicación

Thiourea has been used as a component of lysis buffer for solubilization of the proteins from tissue samples and T-leukemia cells. It has also been used as a component of sample buffer for placental tissue, leaf proteome, and 2D electrophoresis.

Acciones bioquímicas o fisiológicas

Thiourea is an organic compound and its derivatives have antibacterial, antiviral, antifungal and insecticidal property. It is actively used in the drug development against human immunodeficiency virus (HIV) and hepatitis C infection. Thiourea inhibits cyclooxygenase enzyme and effectively reduces prostaglandin E2 (PGE2) and thromboxane (TXB2) production and is antithrombotic in human platelets. It is cytotoxic to vaginal epithelial cells and may function as potent spermicidal agent. Thiourea based derivatives of anticancer drug sorafenib, eliclits antiproliferative activity in human colon cancer cell line, HCT116 cells.

Almacenamiento y estabilidad

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Nota de análisis

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Pictogramas

Environment

Palabra de señalización

Warning

Frases de peligro

Código de clase de almacenamiento

13 - Non Combustible Solids


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Los clientes también vieron

Synthesis and antiplatelet activity of antithrombotic thiourea compounds: biological and structure-activity relationship studies
Lourencco A, et al.
Molecules (Basel), 20(4), 7174-7200 (2015)
Design, synthesis and biological activities of thiourea containing sorafenib analogs as antitumor agents
Yao J, et al.
Bioorganic & Medicinal Chemistry, 20(9), 2923-2929 (2012)
Spontaneous Unexplained Preterm Labor with Intact Membrane: Finding Protein Biomarkers through Placenta Proteome
Electrophoresis-Life Sciences Practical Applications (2018)
Isolation and Identification of Proteins From Potato Leaves
Szajko K
Plant Breeding, 75(1), 29-36 (2017)
Capabilities using 2-D DIGE in proteomics research
Tissue proteomics, 1-18 (2008)

Artículos

This page describes components of rehydration solutions for use in 2-D Electrophoresis with Cytiva products.

Protocolos

This page describes typical rehydration solutions for use in gel electrophoresis with Cytiva products.

This page describes two-dimensional separation of protein samples with Cytiva products.

This page describes two-dimensional separation of protein samples with Cytiva products.

This page describes two-dimensional separation of protein samples with Cytiva products.

Ver todo

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