42602

Propionyl-L-carnitine

≥94.0% (HPLC), suitable for LC/MS

• Sinónimos: (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine propionyl ester, C3-Carnitine, Propanoyl-L-carnitine
• Fórmula empírica (notación de Hill): C₁₀H₁₉NO₄
• Número de CAS: 20064-19-1
• Peso molecular: 217.26
• Número MDL: MFCD00870024
• Código UNSPSC: 12352209
• ID de la sustancia en PubChem: 329756246
• NACRES: NA.26

Propiedades

• Nombre del producto: Propionyl-L-carnitine, ≥94.0% (HPLC)
• Nivel de calidad: 100
• Ensayo: ≥94.0% (HPLC)
• Formulario: powder or crystals
• actividad óptica: [α]/D -23±3°, c = 1 in H₂O
• técnicas: LC/MS: suitable
• impurezas: ≤10% water (calcd. from elemental analysis)
• color: white to off-white
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
• InChI: 1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
• Clave InChI: UFAHZIUFPNSHSL-MRVPVSSYSA-N

Descripción

Descripción general

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

Aplicación

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Acciones bioquímicas o fisiológicas

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable