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900741

Sigma-Aldrich

Gelatin methacryloyl

gel strength 170-195 g Bloom, degree of substitution: 60%

Sinónimos:

GelMA, Gelatin methacrylamide, Gelatin methacrylate, GelMa, Gelatin Methacrylate

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About This Item

Fórmula lineal:
(C40H59N11O13)n
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

100

form

solid

storage temp.

2-8°C

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Application

Gelatin methacrylate can be used to form cross-linked hydrogels for tissue engineering and 3D printing. It has been used for endothelial cell morphogenesis, cardiomyocytes, epidermal tissue, injectable tissue constructs, bone differentiation, and cartilage regeneration. Gelatin methacrylate has been explored in drug delivery applications in the form of microspheres and hydrogels.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Facile one-step micropatterning using photodegradable methacrylated gelatin hydrogels for improved cardiomyocyte organization and alignment.
Tsang K, et al.
Advances in Functional Materials, 25(6), 977-986 (2015)
Covalent attachment of a three-dimensionally printed thermoplast to a gelatin hydrogel for mechanically enhanced cartilage constructs.
Boere KWM, et al.
Acta Biomaterialia, 10(6), 2602-2611 (2014)
Photocrosslinkable gelatin hydrogel for epidermal tissue engineering.
Zhao X, et al.
Advanced Helathcare Materials (2015)
Jason W Nichol et al.
Biomaterials, 31(21), 5536-5544 (2010-04-27)
The cellular microenvironment plays an integral role in improving the function of microengineered tissues. Control of the microarchitecture in engineered tissues can be achieved through photopatterning of cell-laden hydrogels. However, despite high pattern fidelity of photopolymerizable hydrogels, many such materials
Preparation and characterization of gelatin-poly(methacrylic acid) interpenetrating polymeric network hydrogels as a pH-sensitive delivery system for glipizide.
Gupta NV, et al.
Indian Journal of Pharmaceutical Sciences, 69(1), 64-68 (2007)
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Photo-Crosslinkable Gelatin Hydrogel: Versatile Materials for (High Resolution) Additive Manufacturing

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

Three-Dimensional Bioprinting for Tissue and Disease Modeling

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Three-Dimensional Bioprinting for Tissue and Disease Modeling

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

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