I4625

Inosine 5′-monophosphate disodium salt hydrate

from yeast, Grade III, ≥98% (HPLC)

• Synonym(s): 5′-IMP-Na₂, 5′-Inosinic acid disodium salt hydrate, I-5′-P, IMP, Inosinic Acid
• Empirical Formula (Hill Notation): C₁₀H₁₁N₄O₈PNa₂ · xH₂O
• CAS Number: 352195-40-5
• Molecular Weight: 392.17 (anhydrous basis)
• MDL number: MFCD00150372
• UNSPSC Code: 41106305
• PubChem Substance ID: 24896058
• NACRES: NA.51

Properties

• biological source: yeast
• type: Grade III
• Assay: ≥98% (HPLC)
• form: powder
• solubility: water: 50 mg/mL, clear, colorless
• storage temp.: 2-8°C
• SMILES string: [Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)n2cnc3C(=O)NC=Nc23
• InChI: 1S/C10H13N4O8P.2Na.H2O/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• InChI key: KQCIGEIXDXQSGM-MSQVLRTGSA-L

Description

Application

Inosine 5′-monophosphate (IMP) is used as a substrate to study the distribution, specificity and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).

Inosine 5′-monophosphate disodium salt hydrate has been used:

• as a 5′-ribonucleotide tastant compound in taste-detection threshold tests in chicks
• for standard curve generation in high-performance liquid chromatography (HPLC) to quantify IMP from prawn tail tissue samples
• as a component of McCoy′s 5A complete medium for Plasmodium vivax culture

Biochem/physiol Actions

Inosine 5′-monophosphate (IMP) is a dietary nucleotide that is synthesized from adenosine monophosphate (AMP) in eukaryotes. It is a food additive and is essential for intestinal health and immunity.

Inosine monophosphate, or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves