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05164

Supelco

(Aminomethyl)phosphonic acid

PESTANAL®, analytical standard

Synonym(s):

AMPA

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About This Item

Linear Formula:
NH2CH2P(O)(OH)2
CAS Number:
1066-51-9
Molecular Weight:
111.04
Beilstein:
1701219
MDL number:
MFCD00008105
UNSPSC Code:
77101502
PubChem Substance ID:
329747650
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

Assay

≥98.0% (TLC)

shelf life

limited shelf life, expiry date on the label

impurities

≤3.0% water (calc. from elemental analysis)

application(s)

agriculture
environmental

format

neat

SMILES string

NCP(O)(O)=O

InChI

1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)

InChI key

MGRVRXRGTBOSHW-UHFFFAOYSA-N

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Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM2803
BCCL2136
BCCK3466
BCCH3036
BCCG4198

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Seonil Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(10), 3122-3127 (2015-02-26)
Gene knockout (KO) does not always result in phenotypic changes, possibly due to mechanisms of functional compensation. We have studied mice lacking cGMP-dependent kinase II (cGKII), which phosphorylates GluA1, a subunit of AMPA receptors (AMPARs), and promotes hippocampal long-term potentiation
Philip Jean-Richard Dit Bressel et al.
PloS one, 9(11), e111699-e111699 (2014-11-05)
The lateral habenula (LHb) is a small epithalamic structure that projects via the fasciculus retroflexus to the midbrain. The LHb is known to modulate midbrain dopamine (DA) neurons, including inhibition of ventral tegmental area (VTA) neurons via glutamatergic excitation of
Mary L Huff et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(4), 861-873 (2014-09-27)
Recent findings suggest that the mesolimbic dopamine neurons, known to promote cocaine-seeking behavior, are strongly inhibited by a newly characterized region of the midbrain known as the rostromedial tegmental nucleus (RMTg). The RMTg appears to be involved in generating reward-prediction
Martin Puskarjov et al.
Neuropharmacology, 88, 103-109 (2014-09-18)
A robust increase in the functional expression of the neuronal K-Cl cotransporter KCC2 during CNS development is necessary for the emergence of hyperpolarizing ionotropic GABAergic transmission. BDNF-TrkB signaling has been implicated in the developmental up-regulation of KCC2 and, in mature
W Zhou et al.
European psychiatry : the journal of the Association of European Psychiatrists, 29(7), 419-423 (2013-12-11)
Ketamine exerts fast acting, robust, and lasting antidepressant effects in a sub-anesthetic dose, however, the underlying mechanisms are still not fully elucidated. Recent studies have suggested that ketamine's antidepressant effects are probably attributed to the activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)
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