Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

100013

Sigma-Aldrich

4,4′-Dimethoxytrityl chloride

95%

Synonym(s):

DMT-Cl

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
C6H5C(C6H4OCH3)2Cl
CAS Number:
40615-36-9
Molecular Weight:
338.83
Beilstein:
2471942
EC Number:
255-002-6
MDL number:
MFCD00008409
UNSPSC Code:
12352101
PubChem Substance ID:
24846511
NACRES:
NA.22

Assay

95%

form

solid

mp

119-123 °C (lit.)

SMILES string

COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3

InChI

1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3

InChI key

JBWYRBLDOOOJEU-UHFFFAOYSA-N

General description

DMT-Cl is commonly used as a protecting group for various functional groups in organic synthesis.

Application

Hydroxyl protecting group for nucleosides and nucleotides.

Signal Word

Danger

Hazard Statements

H314,H317,H335,H411

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Di-tert-butylsilyl bis(trifluoromethanesulfonate) 97%

Sigma-Aldrich

262021

Di-tert-butylsilyl bis(trifluoromethanesulfonate)

Journal of the American Chemical Society, 115, 4985-4985 (1993)
T Tuschl et al.
Biochemistry, 32(43), 11658-11668 (1993-11-02)
The three guanosines of the central core of a hammerhead ribozyme were replaced by 2-aminopurine ribonucleoside, xanthosine, isoguanosine, inosine, and deoxyguanosine. These analogues were incorporated by automated solid-phase synthesis, with the exception of isoguanosine. This was introduced by ligating a
Y Ueno et al.
Nucleic acids research, 21(19), 4451-4457 (1993-09-25)
The preparation of a nucleotidyl-peptide having a thymidine-5'-yl-(P-O)-serine phosphodiester bond, [H-Ala-Ser(pTpT)-Phe-OH](24) is described. After condensation between the phosphorylated peptide component and an oligonucleotide component, all protecting groups could be removed under neutral conditions without beta-elimination of the pTpT from the
Organoiodinane oxyanions as reagents for the cleavage of a reactive phosphate
Moss RA, et al.
The Journal of Organic Chemistry, 51, 4303-4307 (1986)
Thomas F Scott et al.
Clinical neurology and neurosurgery, 127, 86-92 (2014-12-03)
To describe a "new natural history" of multiple sclerosis (MS), characterizing three patterns of progression in Relapsing MS (RMS) patients during the "treatment era," using newly developed definitions. By utilizing our simple model we intend to predict which patients are
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service