- Possible mechanism of antidepressant effect of L-sulpiride.
Possible mechanism of antidepressant effect of L-sulpiride.
Clinical neuropharmacology (1990-01-01)
G Serra, A Forgione, P S D'Aquila, M Collu, W Fratta, G L Gessa
PMID2199037
RESUMEN
L-Sulpiride is a dopamine (DA)-receptor blocker that acts as an antidepressant at low doses. We have reviewed evidence suggesting that the antidepressant effect of L-sulpiride may depend on the activation of DA transmission secondary to the blockade of DA autoreceptors.