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Merck

H6771

Sigma-Aldrich

2-Hydroxytetradecanoic acid

≥98% (capillary GC)

Sinónimos:

2-Hydroxymyristic acid, DL-α-Hydroxymyristic acid

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About This Item

Fórmula empírica (notación de Hill):
C14H28O3
Número de CAS:
Peso molecular:
244.37
Beilstein/REAXYS Number:
1725369
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.77

assay

≥98% (capillary GC)

lipid type

saturated FAs

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCC(O)C(O)=O

InChI

1S/C14H28O3/c1-2-3-4-5-6-7-8-9-10-11-12-13(15)14(16)17/h13,15H,2-12H2,1H3,(H,16,17)

InChI key

JYZJYKOZGGEXSX-UHFFFAOYSA-N

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Biochem/physiol Actions

An analog of myristic acid that becomes metabolically activated in cells to form 2-hydroxymyristoyl-CoA. Inhibitor of protein myristoylation.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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R Misasi et al.
Clinical immunology and immunopathology, 67(3 Pt 1), 216-223 (1993-06-01)
IgG antibodies reacting with the GM3-comigrating band extracted from pooled AIDS lymphocytes were detected in 33.3% of AIDS patients sera, in 8% of asymptomatic anti-HIV-positive subjects, in none of the sera obtained from asymptomatic anti-HIV-negative drug abusers, from patients with
E B Denner et al.
International journal of systematic and evolutionary microbiology, 51(Pt 3), 827-841 (2001-06-20)
Strain EDIVT, an exopolysaccharide-producing bacterium, was subjected to polyphasic characterization. The bacterium produced copious amounts of an extracellular polysaccharide, forming slimy, viscous, intensely yellow-pigmented colonies on Czapek-Dox (CZD) agar. The culture fluids of the liquid version of CZD medium were
M S Trent et al.
The Journal of biological chemistry, 276(46), 43122-43131 (2001-09-06)
Attachment of the cationic sugar 4-amino-4-deoxy-l-arabinose (l-Ara4N) to lipid A is required for the maintenance of polymyxin resistance in Escherichia coli and Salmonella typhimurium. The enzymes that synthesize l-Ara4N and transfer it to lipid A have not been identified. We
J S Gunn et al.
Infection and immunity, 68(6), 3758-3762 (2000-05-19)
The PhoP-PhoQ two-component system is necessary for the virulence of Salmonella spp. and is responsible for regulating several modifications of the lipopolysaccharide (LPS). Mutagenesis of the transcriptional regulator phoP resulted in the identification of a mutant able to activate transcription
M S Trent et al.
The Journal of biological chemistry, 276(46), 43132-43144 (2001-09-06)
Polymyxin-resistant mutants of Escherichia coli and Salmonella typhimurium accumulate a novel minor lipid that can donate 4-amino-4-deoxy-l-arabinose units (l-Ara4N) to lipid A. We now report the purification of this lipid from a pss(-) pmrA(C) mutant of E. coli and assign

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