COV434

7071909, human ovary, Polygonal & fusiform

• Sinónimos: COV-434 Cells
• UNSPSC Code: 41106514

Propiedades

• product name: COV434, 07071909
• biological source: human ovary
• growth mode: Adherent
• karyotype: Modal chromosome no. 47 (46 - 47)
• morphology: Polygonal & fusiform
• products: Not specified
• receptors: Not specified
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): cancer
• shipped in: dry ice
• storage temp.: −196°C

Descripción

Cell Line Origin

Human ovarian granulosa tumour

Cell Line Description

Human ovarian granulosa tumour cell line established from a solid primary tumour.

Application

COV434 has been used to study:

• the effect of 17β-estradiol on granulosa cell tumor growth, migration and invasion
• if mutant p53 (inactivatible R248Q hotspot mutation) works as a cancer-specific drug target
• the expression of TLR (toll-like receptor) and its function in the cell line

Culture Medium

DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)

Subculture Routine

Split confluent cultures 1:2 to 1:5 i.e. seeding at 2-4x10,000 cells/cm² using trypsin/EDTA; 5% CO₂; 37°C.

Other Notes

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