B5438

Balsalazide disodium salt hydrate

• Sinónimos: 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate
• Fórmula empírica (notación de Hill): C₁₇H₁₃N₃Na₂O₆ · xH₂O
• Número de CAS: 213594-60-6
• Peso molecular: 401.28 (anhydrous basis)
• MDL number: MFCD18632541
• UNSPSC Code: 12352100
• PubChem Substance ID: 329773261
• NACRES: NA.25

Propiedades

• assay: ≥99% (HPLC)
• form: powder
• storage temp.: 2-8°C
• SMILES string: O.[Na+].[Na+].Oc1ccc(cc1C([O-])=O)\N=N\c2ccc(cc2)C(=O)NCCC([O-])=O
• InChI: 1S/C17H15N3O6.2Na.H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;1H2/q;2*+1;/p-2/b20-19+;;;
• InChI key: ZZZXQZHSFPVNCR-HVARVCSCSA-L

Descripción

Biochem/physiol Actions

Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals. Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa. It was also shown to inhibit azoxymethane-induced colon carcinogenesis. In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable