SMB01360

1-MethylpseudoUridine

≥98% (HPLC)

• Sinónimos: 1-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione, N¹-Methylpseudouridine
• Fórmula empírica (notación de Hill): C₁₀H₁₄N₂O₆
• Número de CAS: 13860-38-3
• Peso molecular: 258.23
• MDL number: MFCD10687017
• UNSPSC Code: 41106305
• NACRES: NA.21

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• storage temp.: 2-8°C
• InChI: 1S/C10H14N2O6/c1-12-2-4(9(16)11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,8+/m1/s1
• InChI key: UVBYMVOUBXYSFV-XUTVFYLZSA-N

Descripción

General description

A key aspect of COVID-19 mRNA vaccines is the use of the modified nucleobase Methylpseudouridine to increase their effectiveness. The modified nucleobase helps cloak mRNA vaccines from the immune system, limiting their undesired immune stimulation, and in certain circumstances may also enhance the synthesis of antigens.

Application

Vaccine development

Other Notes

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Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable