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Key Documents

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32544

Supelco

Fenbendazole sulfone

VETRANAL®, analytical standard

Sinónimos:

5-Benzenesulfonyl-1H-benzoimidazol-2-yl)carbamic acid methyl ester, Methyl 5-(phenylsulfonyl)-2-benzimidazolecarbamate

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About This Item

Fórmula empírica (notación de Hill):
C15H13N3O4S
Número de CAS:
54029-20-8
Peso molecular:
331.35
Beilstein/REAXYS Number:
703211
MDL number:
MFCD00797921
UNSPSC Code:
41116107
PubChem Substance ID:
329754020
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)S(=O)(=O)c3ccccc3

InChI

1S/C15H13N3O4S/c1-22-15(19)18-14-16-12-8-7-11(9-13(12)17-14)23(20,21)10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

InChI key

UAFDGCOOJPIAHN-UHFFFAOYSA-N

Categorías relacionadas

General description

Chemical structure: benzimidazole

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Referencia del producto
Descripción
Precios

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCL5577
BCCJ5710
BCCF6820
BCCD2334
BCBZ7731

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Fenbendazole

T G Watson et al.
Research in veterinary science, 38(2), 231-233 (1985-03-01)
The pharmacokinetics of oxfendazole (OFZ) in red deer (Cervus elaphus) was examined. OFZ, administered per os at 4.53 mg kg-1, was extracted in ether from plasma and identified and concentrations estimated by high pressure liquid chromatography. Irrespective of whether the
S E Marriner et al.
American journal of veterinary research, 42(7), 1143-1145 (1981-07-01)
Pharmacokinetics of oxfendazole and its sulfone metabolite were determined in 6 sheep. Oxfendazole achieved mean peak plasma concentrations of 0.76 micrograms/ml at 30 hours after oral administration of oxfendazole (10 mg/kg of body weight), and concentrations were detectable for up
J Landuyt et al.
Biomedical chromatography : BMC, 7(2), 78-81 (1993-03-01)
A high performance liquid chromatographic (HPLC) method for the determination of the anthelminthic pro-benzimidazole febantel and its major metabolites in lamb plasma has been developed. Samples were extracted after addition of albendazole as internal standard, NH4OH and distilled diethyl ether.
P Viviani et al.
Journal of veterinary pharmacology and therapeutics, 41(3), 476-484 (2018-02-22)
Parasitic diseases have a significant impact on livestock production. Nematodicidal drugs, such as fenbendazole (FBZ) or its oxidized metabolite oxfendazole (OFZ), can be used along with the trematodicidal triclabendazole (TCBZ), to broaden the spectrum of anthelmintic activity. However, co-exposure to
Francesca Accioni et al.
Journal of agricultural and food chemistry, 67(1), 520-530 (2018-12-06)
In this work, a restricted access volatile supramolecular solvent (RAM-VOL-SUPRAS) directly synthesized in milk is proposed for the first time for the simultaneous extraction and cleanup of benzimidazole anthelmintic drugs in milk meant for human consumption. The RAM-VOL-SUPRAS was formed
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