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Merck

21980

Sigma-Aldrich

Cardiogreen

for microscopy

Sinónimos:

Foxgreen, IC Green, Indocyanine green

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About This Item

Fórmula empírica (notación de Hill):
C43H47N2NaO6S2
Número de CAS:
Peso molecular:
774.96
Beilstein/REAXYS Number:
4115884
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
MA.02

grade

for microscopy

Quality Level

form

powder

color

green to very dark green

solubility

water: 0.01 g/10 mL

ε (extinction coefficient)

≥115 at 386-396 nm in water
≥2000 at 774-784 nm in water
≥900 at 712-722 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].CC1(C)/C(=C\C=C\C=C\C=C\C2=[N+](CCCCS([O-])(=O)=O)c3ccc4ccccc4c3C2(C)C)N(CCCCS([O-])(=O)=O)c5ccc6ccccc6c15

InChI

1S/C43H48N2O6S2.Na/c1-42(2)38(44(28-14-16-30-52(46,47)48)36-26-24-32-18-10-12-20-34(32)40(36)42)22-8-6-5-7-9-23-39-43(3,4)41-35-21-13-11-19-33(35)25-27-37(41)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1

InChI key

MOFVSTNWEDAEEK-UHFFFAOYSA-M

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General description

Cardiogreen is a dye used for microscopy. This dye has its maximum extinction at the same wavelength as reduced and oxygenated haemoglobin meet making it possible to record the oxygen saturation in blood. This dye has no side-effects.

Application

Cardiogreen was injected in animals intravenously for dynamic optical imaging system to study the capability of capturing the in vivo biodistribution kinetics.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

A diagnostic aid in the determination of hepatic function

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Determination of cardiac output with cardio green in a direct writing colorimeter.
B HYSING et al.
Scandinavian journal of clinical and laboratory investigation, 14, 430-434 (1962-01-01)
C.M. Leevy et al.
Probl. Liver Dis. (Review), 42-42 (1979)
Elizabeth M C Hillman et al.
Nature photonics, 1(9), 526-530 (2008-11-01)
Optical molecular imaging in small animals harnesses the power of highly specific and biocompatible contrast agents for drug development and disease research1-7. However, the widespread adoption of in vivo optical imaging has been inhibited by its inability to clearly resolve
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