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Key Documents

16-235

Sigma-Aldrich

Anti-phospho-erbB-2/HER-2 (Tyr1248) Antibody, Alexa Fluor 488

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

ALEXA FLUOR 488

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat

manufacturer/tradename

Upstate®

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

phosphorylation (pTyr1248)

Specificity

Predicted to cross react with rat based on conservation of immunogenic sequence
the activated form of Erb B2/HER-2 oncoprotein

Immunogen

Synthetic phosphopeptide, residues 1243-1255, corresponding to a major autophosphorylation (Tyr1248) site of human Erb B2/HER-2 (C-AENPEpYLGLDVPV)

Application

Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

Kinases & Phosphatases
This Anti-phospho-erbB-2/HER-2 (Tyr1248) Antibody, Alexa Fluor 488 is validated for use in FC, IC for the detection of phospho-erbB-2/HER-2 (Tyr1248).

Quality

Routinely evaluated by immunostaining of EGF treated A431 cells

Target description

185kDa

Physical form

ImmunoAffinity Purified

Storage and Stability

1 year at 4°C from date of shipment

Analysis Note

Control
Negative Control: Catalog # 16-237, Normal Rabbit IgG, Alexa Fluor 488-conjugate.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Alexa Fluor is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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