1.07069

Phloroglucinol

(1,3,5-trihydroxybenzene) for analysis

• Sinónimos: Phloroglucinol, 1,3,5-Trihydroxybenzene
• Fórmula lineal: C₆H₃-1,3,5-(OH)₃
• Número de CAS: 108-73-6
• Peso molecular: 126.11
• MDL number: MFCD00002286
• UNSPSC Code: 12352104
• EC Index Number: 203-611-2
• NACRES: SE.11

Propiedades

• Quality Level: 100
• assay: ≥99.0% (GC)
• form: crystals; fine powder
• potency: 4000 mg/kg LD₅₀, oral (Rat)
• mp: 217-220 °C
• solubility: 10 g/L
• bulk density: 560 kg/m³
• storage temp.: 15-25°C
• InChI: 1S/C6H6O3/c7-4-1-5(8)3-6(9)2-4/h1-3,7-9H
• InChI key: QCDYQQDYXPDABM-UHFFFAOYSA-N

Descripción

Application

• Biomimetic Synthesis and Chemical Proteomics Reveal the Mechanism of Action and Functional Targets of Phloroglucinol Meroterpenoids.: This study explores the synthesis and mechanisms of phloroglucinol-based compounds, focusing on their biological activity and potential therapeutic applications. It highlights the use of chemical proteomics to identify functional targets, contributing to the understanding of phloroglucinol′s role in medicinal chemistry (Bracken et al., 2024).


• Clinical efficacy and metabolomics study of Wendan Decoction in the treatment of phlegm-dampness obstructive sleep apnea-hypopnea syndrome with type 2 diabetes mellitus.: This research investigates the clinical effects and metabolic pathways influenced by Wendan Decoction, which includes phloroglucinol as a component. The study uses metabolomics to elucidate the biochemical interactions and therapeutic effects in patients with sleep apnea and diabetes (Zhou et al., 2023).


• Metabolomics characterizes early metabolic changes and markers of tolerant Eucalyptus ssp. clones against drought stress.: This paper employs metabolomics to study drought tolerance in Eucalyptus clones, identifying early metabolic changes involving phloroglucinol derivatives. The findings enhance the understanding of plant resilience mechanisms under stress conditions (Noleto-Dias et al., 2023).


• Phloroglucinol and Its Derivatives: Antimicrobial Properties toward Microbial Pathogens.: This review compiles data on the antimicrobial activities of phloroglucinol and its derivatives, emphasizing their potential as bioactive agents in combating various microbial pathogens. The study covers the spectrum of their efficacy and possible applications in microbial control (Khan et al., 2022).


• Anti-Inflammatory Markers of Hops Cultivars (Humulus lupulus L.) Evaluated by Untargeted Metabolomics Strategy.: This research identifies anti-inflammatory compounds in hops, including phloroglucinol derivatives, using an untargeted metabolomics approach. The study provides insights into the biochemical basis of the anti-inflammatory properties of hops (Nicacio et al., 2022).

Analysis Note

Color (visual): white to yellowish
Appearance of substance (visual): fine powder or crystals
Assay (GC, area%): ≥ 99.0 % (a/a)
Loss on Drying (105°C): ≤ 1.0 %
Sulfated ash: ≤ 0.1 %
Diresorcinol: passes test
Identity (IR): passes test

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H317,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable