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568864

Sigma-Aldrich

Fluorescein O-methacrylate

95%

Sinónimos:

3′-Methacryloxyspirobenzo[c]-furan[1,9’]xanthen-3-one, Methacryloyloxy fluorescein

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About This Item

Fórmula empírica (notación de Hill):
C24H16O6
Número de CAS:
480439-15-4
Peso molecular:
400.38
MDL number:
MFCD04974071
UNSPSC Code:
12352103
PubChem Substance ID:
24880228
NACRES:
NA.23

assay

95%

form

solid

mp

227-232 °C (lit.)

λmax

490 nm

storage temp.

2-8°C

SMILES string

CC(=C)C(=O)Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C24H16O6/c1-13(2)22(26)28-15-8-10-19-21(12-15)29-20-11-14(25)7-9-18(20)24(19)17-6-4-3-5-16(17)23(27)30-24/h3-12,25H,1H2,2H3

InChI key

YMHPNLUYVDEYCI-UHFFFAOYSA-N

Categorías relacionadas

General description

Fluorescein O-methacrylate is a pH sensitive dye with a fluorescent monomer. It can be characterized by an excitation spectra at 490 nm and an emission spectra at 520 nm. It has fluorescein that acts as an indicator with the least negative charges. Its properties include biocompatibility, non-toxicity and good dispersion in aqueous solution.

Application

Fluorescein O-methacrylate can be used as a marker that can be incorporated into the nanoparticle complexes for biological applications. It forms environmentally responsive materials that can be used as probes for cellular imaging.
Fluorescent monomer

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Disposable fluorescence optical pH sensor for near neutral solutions
Ferrari L, et al.
Sensors, 13(1), 484-499 (2013)
Synthesis and characterization of multifunctional Fe3O4/poly (fluorescein O-methacrylate) core/shell nanoparticles
Govindaiah P, et al.
Journal of Colloid and Interface Science, 379(1), 27-32 (2012)
Zhenhua Li et al.
Nanoscale, 9(40), 15407-15415 (2017-10-05)
Protein modified functional surfaces have been applied extensively in the field of biomaterials and medicine. Regulation of the amount and activity of proteins on the material surface is always a challenge and a key research issue. A multifunctional micro/nano-composite based
Functionalized plasmonic- fluorescent nanoparticles for imaging and detection
Saha A, et al.
The Journal of Physical Chemistry C, 113(43), 18492-18498 (2009)
Aydan Dag et al.
Biomacromolecules, 20(8), 2962-2972 (2019-07-18)
An important requirement to decrease the side effects of chemotherapy drugs is to develop nanocarriers with precise biological functions. In this work, a set of glyconanoparticles was prepared via self-assembly of amphiphilic glycoblock copolymers for the targeted delivery of a
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