186651

18-Crown-6

99%

• Sinónimos: 1,4,7,10,13,16-Hexaoxacyclooctadecane
• Fórmula empírica (notación de Hill): C₁₂H₂₄O₆
• Número de CAS: 17455-13-9
• Peso molecular: 264.32
• Beilstein/REAXYS Number: 1619616
• EC Number: 241-473-5
• MDL number: MFCD00005113
• UNSPSC Code: 12352005
• PubChem Substance ID: 24851233
• NACRES: NA.22

Propiedades

• assay: 99%
• form: solid
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• mp: 42-45 °C (lit.)
• greener alternative category: , Aligned
• SMILES string: O1CCOCCOCCOCCOCCOCC1
• InChI: 1S/C12H24O6/c1-2-14-5-6-16-9-10-18-12-11-17-8-7-15-4-3-13-1/h1-12H2
• InChI key: XEZNGIUYQVAUSS-UHFFFAOYSA-N

Descripción

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalysis. Find details here.

18-Crown-6 is the simplest crown ether that can be prepared by reacting triethylene glycol with triethylene glycol dichloride in the presence of potassium hydroxide as base.

Application

18-Crown-6 may be used to catalyze the N-alkylation of heterocyclic compounds and allylation of functionalized aldehydes.

Additive for greener etherification using KF-alumina.

Additive for greener etherification using KF-alumina.

Synthesis of diaryl ethers, diaryl thioethers, and diarylamines mediated by potassium fluoride-alumina and 18-crown-6

Phase-transfer catalyst used in a chemoselective reduction of fused tetrazoles with NaBH₄ and potassium hydroxide.

Puede ser útil como catalizador de transferencia de fase.

Other Notes

Poliéteres macrocíclicos con repetición de unidades (-CH₂CH₂O). Los compuestos son ionofóricos (forman compuestos estables con cationes).

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves