Improved synthesis of chalcones under ultrasound irradiation.

Improved synthesis of chalcones under ultrasound irradiation.

Ultrasonics sonochemistry (2002-10-10)

Ji-Tai Li, Wen-Zhi Yang, Shu-Xiang Wang, Sheng-Hui Li, Tong-Shuang Li

ABSTRACT

Claisen-Schmidt condensation of acetophenone with aromatic aldehydes catalyzed by pulverized KOH and KF-Al2O3 results chalcones in 52-97% and 83-98% yields respectively in alcoholic solvent under ultrasound irradiation.

MATERIALS

Product Number

Brand

Product Description

484016

Sigma-Aldrich

Potassium hydroxide, reagent grade, 90%, flakes

60370

Sigma-Aldrich

Potassium hydroxide, puriss. p.a., ≥86% (T), pellets

221473

Sigma-Aldrich

Potassium hydroxide, ACS reagent, ≥85%, pellets

30603

Sigma-Aldrich

Potassium hydroxide, pellets, reag. Ph. Eur., ≥85%

06005

Sigma-Aldrich

Potassium hydroxide, puriss., meets analytical specification of Ph. Eur., BP, 85-100.5%, pellets

06103

Sigma-Aldrich

Potassium hydroxide, technical, ≥85%, powder

911062

Sigma-Aldrich

Potassium hydroxide, free-flowing, Redi-Dri^™, ACS reagent, ≥85%, pellets

306568

Sigma-Aldrich

Potassium hydroxide, semiconductor grade, pellets, 99.99% trace metals basis (Purity excludes sodium content.)