Skip to Content
Merck
  • Fabrication, properties and bioapplications of cellulose/collagen hydrolysate composite films.

Fabrication, properties and bioapplications of cellulose/collagen hydrolysate composite films.

Carbohydrate polymers (2013-02-13)
Ying Pei, Juan Yang, Pan Liu, Min Xu, Xianzheng Zhang, Lina Zhang
ABSTRACT

In this work, a series of cellulose/collagen hydrolysate (RC/CH) films were prepared in NaOH/urea aqueous solution via a simple, low-cost and green pathway. To overcome the disadvantages (brittleness, poor water resistance) of CH as biomaterials, CH was combined with regenerated cellulose (RC) film to construct RC/CH composite materials, leading to vast improvement of the water resistance of CH. Crosslinking with genipin further improved the mechanical properties of the RC/CH films in the wet state. Their structure and properties were characterized by elemental analysis, Fourier transform infra-red (FT-IR) spectra, ultraviolet-visible (UV-vis), scanning electron microscopy (SEM), amino acid analysis, tensile testing, cell adhesion and toxicity tests. The mechanical properties and water resistance of the crosslinked RC/CH films were significantly improved, which made collagen hydrolysate as biomaterial could be used at wet state. Moreover, the RC/CH films exhibited good biocompatibility by proliferation of COS7 cells on the surface, supporting cell adhesion and growth.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Sodium hydroxide solution, 4 M
Sigma-Aldrich
Sodium hydroxide solution, 7 M
Sigma-Aldrich
Sodium hydroxide solution, 1 M
Sigma-Aldrich
Sodium hydroxide solution, 6 M
Sigma-Aldrich
Sodium hydroxide solution, 0.01 M
Sigma-Aldrich
Sodium hydroxide solution, 0.05 M
Sigma-Aldrich
Sodium hydroxide solution, 0.2 M
Supelco
Sodium hydroxide concentrate, 0.1 M NaOH in water (0.1N), Eluent concentrate for IC
Sigma-Aldrich
Sodium hydroxide solution, BioUltra, for molecular biology, 10 M in H2O
Sigma-Aldrich
Sodium hydroxide, BioUltra, for luminescence, ≥98.0% (T), pellets
Supelco
Sodium hydroxide solution, 49-51% in water, eluent for IC
Sigma-Aldrich
Sodium hydroxide, ultra dry, powder or crystals, 99.99% trace metals basis
Sigma-Aldrich
Sodium hydroxide solution, 1.0 N, BioReagent, suitable for cell culture
Sigma-Aldrich
Sodium hydroxide, anhydrous, free-flowing, Redi-Dri, reagent grade, ≥98%, pellets
Sigma-Aldrich
Sodium hydroxide, reagent grade, 97%, powder
Sigma-Aldrich
Sodium hydroxide, puriss. p.a., ACS reagent, K ≤0.02%, ≥98.0% (T), pellets
Sigma-Aldrich
Sodium hydroxide, reagent grade, ≥98%, pellets (anhydrous)
Sigma-Aldrich
Sodium hydroxide solution, 5.0 M
Sigma-Aldrich
Sodium hydroxide, ACS reagent, ≥97.0%, pellets
Sigma-Aldrich
Sodium hydroxide, puriss. p.a., ACS reagent, reag. Ph. Eur., K ≤0.02%, ≥98%, pellets
Sigma-Aldrich
Sodium hydroxide, BioXtra, ≥98% (acidimetric), pellets (anhydrous)
Sigma-Aldrich
Sodium hydroxide solution, purum, ≥32%
Sigma-Aldrich
Sodium hydroxide, puriss., meets analytical specification of Ph. Eur., BP, NF, E524, 98-100.5%, pellets
Sigma-Aldrich
Sodium hydroxide solution, 50% in H2O
Sigma-Aldrich
Sodium hydroxide, reagent grade, 97%, flakes
Sigma-Aldrich
Sodium hydroxide, beads, 16-60 mesh, reagent grade, 97%
Sigma-Aldrich
Sodium hydroxide, SAJ first grade, ≥95.0%
Sigma-Aldrich
Sodium hydroxide solution, 0.1 M
Sigma-Aldrich
Sodium hydroxide, JIS special grade, ≥96.0%
Sigma-Aldrich
Sodium hydroxide, pellets, semiconductor grade, 99.99% trace metals basis