N6879

α-Nicotinamide adenine dinucleotide, reduced disodium salt

≥90%

• Synonym(s): α-DPNH, α-Dihydrodiphosphopyridine nucleotide, α-Dihydronicotinamide adenine dinucleotide, α-NADH
• Linear Formula: C₂₁H₂₇N₇O₁₄P₂Na₂
• CAS Number: 108321-31-9
• Molecular Weight: 709.40
• MDL number: MFCD00079521
• UNSPSC Code: 41106305
• PubChem Substance ID: 24897797
• NACRES: NA.51

Properties

• Assay: ≥90%
• form: powder
• impurities: ≤3% β-isomer
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@@H]3O[C@@H]([C@@H](O)[C@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
• InChI: 1S/C21H29N7O14P2.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;/q;2*+1/p-2/t10-,11+,13-,14+,15-,16+,20+,21+;;/m1../s1
• InChI key: QRGNQKGQENGQSE-WPVKCSLBSA-L

Description

Application

α-Nicotinamide adenine dinucleotide, reduced (α-NADH) may be used as a cosubstrate to assess the specificity and kinetics of NAD+/NADH and NADP+/NADPH dependent enzymes and to assess the dynamics of nucleotides in ion channels such as voltage-dependent mitochondrial ion channels (VDAC).

Other Notes

Analog of β-NADH, chemically reduced

Caution

This is not the common NADH required in the usual enzyme systems.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves