F9932

FFN511 trifluoroacetate salt hydrate

≥98% (HPLC)

• Synonym(s): 8-(2-Amino-ethyl)-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one trifluoroacetate salt hydrate, 9-(2-aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-11-one trifluoroacetate salt hydrate
• Empirical Formula (Hill Notation): C₁₇H₂₀N₂O₂ · F₃CCO₂H · xH₂O
• CAS Number: 1004548-96-2
• Molecular Weight: 398.38 (anhydrous basis)
• MDL number: MFCD18632543
• UNSPSC Code: 12352200
• PubChem Substance ID: 329799792
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: yellow
• solubility: DMSO: ≥20 mg/mL
• storage temp.: 2-8°C
• SMILES string: O.OC(=O)C(F)(F)F.NCCC1=CC(=O)Oc2c3CCCN4CCCc(cc12)c34
• InChI: 1S/C17H20N2O2.C2HF3O2.H2O/c18-6-5-11-10-15(20)21-17-13-4-2-8-19-7-1-3-12(16(13)19)9-14(11)17;3-2(4,5)1(6)7;/h9-10H,1-8,18H2;(H,6,7);1H2
• InChI key: RRBOSSKRCWVUPA-UHFFFAOYSA-N

Description

Biochem/physiol Actions

FFN511 is a fluorescent substrate for the synaptic vesicle monoamine transporters. FFN511 is used as an optical tracer of dopamine, a fluorescent false neurotransmitter (FFN) to visualize dopamine release from individual presynaptic terminals using time-lapse microscopsy fluorescence. The probe is sufficiently fluorescent so as to provide resolution of individual dopamine terminals at concentrations that do not interfere with normal catecholamine accumulation and transmission. FFN511 is compatible with GFPbased tags, the FM1-43 endocytic marker (Synapto Green), and other optical probes.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable