M0300000

Menadione

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): 2-Methyl-1,4-naphthoquinone, Vitamin K₃
• Empirical Formula (Hill Notation): C₁₁H₈O₂
• CAS Number: 58-27-5
• Molecular Weight: 172.18
• Beilstein: 1908453
• MDL number: MFCD00001681
• UNSPSC Code: 41116107
• PubChem Substance ID: 329817767
• NACRES: NA.24

Properties

• biological source: synthetic
• grade: pharmaceutical primary standard
• Agency: EP
• API family: menadione
• form: solid
• manufacturer/tradename: EDQM
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• mp: 105-107 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC1=CC(=O)c2ccccc2C1=O
• InChI: 1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
• InChI key: MJVAVZPDRWSRRC-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Menadione, a fat-soluble vitamin, is an antihemorrhagic compound that plays an important role in blood coagulation. It takes part in blood clotting by activating prothrombin, the thrombin precursor.

Application

Menadione may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometry techniques.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H315,H317,H319,H335,H410
• Precautionary Statements: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable