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  • Efficient synthesis of fused bicyclic glutarimides. Its application to (+/-)-alloyohimbane and louisianin D.

Efficient synthesis of fused bicyclic glutarimides. Its application to (+/-)-alloyohimbane and louisianin D.

Organic letters (2006-06-30)
Hung-Wei Chen, Ru-Ting Hsu, Meng-Yang Chang, Nein-Chen Chang
ABSTRACT

[reaction: see text] The reaction of alpha-sulfonyl acetamide 1 with various cyclic unsaturated esters 2 to fused bicyclic glutarimides is reported. Syntheses of (+/-)-alloyohimbane (4) and louisianin D (5) have been accomplished.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Glutarimide, 98%