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  • Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor.

Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor.

Organic letters (2000-05-11)
A J Phillips, Y Uto, P Wipf, M J Reno, D R Williams
PMID10804580
ABSTRACT

[formula: see text] A mild and highly efficient cyclization of beta-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from beta-hydroxy amides is also presented.