Fate of desmosomal proteins in apoptotic epidermal cells.

Fate of desmosomal proteins in apoptotic epidermal cells.

Methods in molecular biology (Clifton, N.J.) (2004-10-27)

Jörg Weiske, Otmar Huber

ABSTRACT

In epidermal cells desmosomes represent major sites of basolateral cell-cell contacts that play an important role for epidermal homeostasis. Excess or damaged cells are often removed by apoptosis. To release apoptotic cells from the tissue, intercellular contacts have to be broken. Here detailed protocols to analyze desmosomal proteins in apoptotic cells are described.

MATERIALS

Product Number

Brand

Product Description

264155

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Caspase-3 Inhibitor II, The Caspase-3 Inhibitor II, also referenced under CAS 210344-95-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.

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