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Key Documents

SRP0489

Sigma-Aldrich

PLA2G12B human

recombinant, expressed in mammalian cells, ≥60% (SDS-PAGE)

Synonym(s):

FKSG71, GXIIB, Phospholipase A2 G12

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

recombinant

expressed in mammalian cells

Assay

≥60% (SDS-PAGE)

form

aqueous solution

mol wt

21.1 kDa

packaging

pkg of 10 and 20 μg

NCBI accession no.

NM_032562

UniProt accession no.

Q9BX93

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PLA2G12B(84647)

General description

Human PLA2G12B (GenBank Accession No. NM_032562), amino acids 20-295 (end) with C-terminal His tag, MW=21.1 kDa, expressed in a mammalian cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Physical form

Fomulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM Imidazole, and 20% Glycerol.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H360D

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marianne Berg et al.
Molecular cancer, 9, 100-100 (2010-05-13)
Estimates suggest that up to 30% of colorectal cancers (CRC) may develop due to an increased genetic risk. The mean age at diagnosis for CRC is about 70 years. Time of disease onset 20 years younger than the mean age

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