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F8506

Sigma-Aldrich

N-Formyl-Met-Phe

≥97% (HPLC)

Synonym(s):

Neutrophil Dysfunction Test Peptide

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About This Item

Empirical Formula (Hill Notation):
C15H20N2O4S
CAS Number:
Molecular Weight:
324.40
MDL number:
UNSPSC Code:
12352200

Assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CSCCC(NC=O)C(=O)NC(Cc1ccccc1)C(O)=O

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E Schöpf et al.
International archives of allergy and applied immunology, 82(3-4), 380-382 (1987-01-01)
Atopic dermatitis (AD) is characterized by many signs of immunodeficiency. Our interest was to investigate if there are also alterations of the chemiluminescence (CL) response of polymorphonuclear leukocytes (PMN) as a measure of the release of toxic oxygen radicals. Isolated
I R Cooke et al.
Cell and tissue research, 253(1), 69-76 (1988-07-01)
The distribution of FMRFamide-like immunoreactive neurons in the nervous system of the slug Limax maximus was studied using immunohistochemical methods. Approximately one thousand FMRFamide-like immunoreactive cell bodies were found in the central nervous system. Ranging between 15 micron and 200
Polarization assay studies of human neutrophil motility.
S Tsuda et al.
The Journal of dermatology, 15(2), 116-122 (1988-04-01)
L T Williams et al.
Proceedings of the National Academy of Sciences of the United States of America, 74(3), 1204-1208 (1977-03-01)
Synthetic N-formylmethionyl peptides are chemotactic attractants for human polymorphonuclear leukocytes. The well-defined structure-activity relationship of these peptides in eliciting a chemotactic response suggests that the interaction of the peptides with a specific cellular binding site may initiate chemotaxis. By using
D F Jadwin et al.
American journal of clinical pathology, 76(4), 395-402 (1981-10-01)
The described procedure permits assessment of the neutrophil shape change response to formyl-methionyl peptides added directly to EDTA anticoagulated whole blood. Response is monitored by counting the resultant number of "bipolar" neutrophil forms present on stained blood films. The preparation

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